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CADSTAR
Limited free evaluation version available (300 pins/50 components).
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DipTrace
Limited free evaluation version available (300 pins).
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Eagle
EAGLE free download is a limited version for hobbyists including 2 schematic sheets, 2 signal layers, and an 80cm2 (12.4in2) board area.
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FreePCB
Freeware.
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KiCad
Freeware.
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ZenitPCB Layout
Freeware.